Active Ingredients: Estradiol
Representative Names: Estrace, Gynodiol
Note: The below information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of Estradiol is safe, appropriate, or effective for you. Consult your doctor before you buy Estradiol online.

What is Estradiol?
The medication are estrogens that are essential for maintaining normal female functions. It is normally produced by the ovaries. After menopause, the ovaries decrease their production of this hormone. Estrogens can help relieve symptoms of the menopause (hot flashes, night sweats, mood changes, and vaginal dryness and irritation), and help to prevent the onset of osteoporosis (a loss of bone mass, so that bones become brittle and easily broken). This hormones can also help improve female functions in women with hormonal imbalance or problems with their ovaries. They may also be given to certain men or women with inoperable breast cancers or prostate cancer. Occasionally Estradiol are used for other purposes.

What should I check before I use Estradiol?
Please verify if you have any of these conditions: asthma, blood vessel disease, blood clotting disorder, or suffered a stroke, breast, cervical, endometrial or uterine cancer, diabetes, fibroids in the womb, or endometriosis, heart, kidney or liver disease, high blood lipids or cholesterol, high blood pressure, high level of calcium in the blood, hysterectomy, mental depression, migraine, porphyria, tobacco smoker, vaginal bleeding, an unusual or allergic reaction to estrogens, other hormones, medicines, foods, dyes, or preservatives, pregnant or trying to get pregnant, breast-feeding.

How should I use Estradiol?
Take the tablets by mouth and with a glass of water to help you swallow the tablets. They can also be taken with food or milk if they upset your stomach. Follow the directions on the label and take tbe doses at regular intervals.
Contact your doctor regarding the use of Estradiol in children as special care may be needed.

What if I miss a dose of Estradiol?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. There should be an interval of at least 12 hours between doses.

What drug(s) may interact with this medication?
Medications for diabetes, methotrexate, mineral oil, phenytoin, raloxifene or tamoxifen, rifabutin, rifampin, or rifapentine, some medications for treating migraines, theophylline, thyroid hormones, topiramate, tricyclic antidepressants, warfarin, some antibiotics used to treat infections, some medications used to treat HIV (human immunodeficiency virus) infection or AIDS, ascorbic acid/vitamin C supplements, barbiturates or benzodiazepines used for inducing sleep or treating seizures (convulsions), bromocriptine, carbamazepine, cimetidine, clofibrate, cyclosporine, dantrolene, grapefruit juice, griseofulvin, hormones, hydrocortisone, cortisone, or prednisolone, imipramine or some other antidepressants, isoniazid (INH).
On the questionnaire needed to buy Estradiol, inform of all medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your doctor if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medication works. Check with your doctor before stopping or starting any of your medications.

What side effects may I notice from using Estradiol?
Side effects that you should report to your doctor as soon as possible: breakthrough bleeding and spotting, breast enlargement, tenderness, unusual discharge or milk production, chest pain, leg, arm or groin pain, nausea, vomiting, severe headaches, stomach or abdominal pain (severe), sudden shortness of breath, swelling of the hands, feet or ankles, or rapid weight gain, vision or speech problems, yellowing of the eyes or skin.
Side effects that usually do not require medical attention (report to your doctor if they continue or are bothersome): change in sexual desire, mild stomach upset, mood changes, anxiety, depression, frustration, anger, or emotional outbursts, increased or decreased appetite, skin rash, acne, or brown spots on the face, tiredness, vaginal yeast infection (irritation and white discharge), weight gain.

What precautions should I take while taking Estradiol?
Visit your doctor for regular checks on your progress. You should have a complete check-up every six months. You will also need a regular breast and pelvic exam and 'Pap' smear while on this medication therapy. You should also discuss the need for regular mammograms with your doctor, and follow their guidelines for these tests. If you have any unusual bleeding contact your doctor for advice.
If you have any reason to think you are pregnant, stop taking the medication at once and contact your doctor.
Estradiol can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor if you feel you are retaining fluid.
Tobacco smoking increases the risk of getting a blood clot or having a stroke while you are on this medication, especially if you are more than thirty-five years old. It is strongly recommended NOT to smoke.
In women who still have their uterus, the medication can increase the risk of developing a condition known as endometrial hyperplasia, that may lead to cancer of the lining of the uterus. Taking another hormone drug called progestins, with estrogens can lower the risk of developing this condition. Therefore, if your uterus has not been removed by a hysterectomy, your doctor may prescribe this hormone for you to take together with your estrogen. You should know, however, that taking this 2 hormones together (estrogens with progestins) may have additional health risks. You should discuss the use of these with your doctor to determine the benefits and risks for you.
If you wear contact lenses and notice any visual changes, or if the contact lenses begin to feel uncomfortable, consult your eye care specialist.
If you are going to have elective surgery, you may need to stop taking your medication 1 month beforehand. Consult your doctor for advice prior to scheduling the surgery.

Can I overdose with Estradiol?
If overdose is suspected, contact your local poison control center or emergency room immediately.

Where can I keep my Estradiol?
Keep out of the reach of children. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medication after the expiration date.

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