Valtrex Information

Active Ingredients: Valacyclovir
Representative Names: Valtrex

Note: The below information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of valtrex is safe, appropriate, or effective for you. Consult your healthcare professional before you buy valtrex online.

What is Valtrex?
is an antiviral agent. Valtrex treats herpes zoster infection (shingles) or genital herpes infection. Valtrex is not a cure; it will help the sores heal faster and relieve the pain or discomfort. Valtrex can also be used to help prevent a genital herpes infection from coming back. Valtrex might help prevent genital herpes from being passed on to a partner who does not have genital herpes if it is used with 'safer sex' practices.

Valtrex comes in 500 milligrams and 1-gram (1000mg) caplets. Its shape is oblong and it's colored dark blue in both concentrations. The 500-milligram caplet is smaller in size than the one-gram caplet. The caplets come with an easily recognizable engraving that states Valtrex 500 and Valtrex 1 gram.

What should my I check before I take Valtrex?
Please verify if you have any of these conditions: acquired immunodeficiency syndrome (AIDS), any other condition that may weaken the immune system, dehydration, kidney disease, an unusual or allergic reaction to valacyclovir, acyclovir, ganciclovir, valganciclovir, other medicines, foods, dyes, or preservatives, pregnant or trying to get pregnant, breast-feeding.

How should I take Valtrex?
Take Valtrex caplets by mouth. Follow the directions on the prescription label. Swallow whole with a full glass of water. You can take Valtrex with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Finish the full course prescribed by your prescriber or health care professional even if you think your condition is better. Do not stop taking except on your prescriber's advice.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose of Valtrex?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with Valtrex?
cimetidine, fosphenytoin, phenytoin, probenecid.

On the questionaire needed to buy Valtrex, inform of all medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also include if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

Where can I keep my Valtrex?
Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.

About Herpes Simplex Virus:
Over 80 known viruses exist within the Herpes family. Of these, 8 are known to cause disease in humans, the most common being Herpes Simplex Virus Type-1 (HSV-1) and type-2 (HSV-2). HSV-1 and HSV-2 look identical under the microscope, and either type can infect the mouth or genitals. Usually, however, HSV-1 occurs above the waist, and HSV-2 below the waist :

- Herpes Simplex Virus Type-1 (HSV-1) - commonly causes herpes labialis (also called oral herpes, cold sores or fever blisters), which is a highly infectious open sore that crust over before healing. Although less probable, HSV-1 can also cause genital herpes.
- Herpes Simplex Virus Type-2 (HSV-2) - a contagious viral infection primarily causing genital herpes in men and women. The telltale signs and symptoms of genital herpes include recurrent clusters of blisters, bumps and rashes in the genital areas. HSV-2 can also be responsible for herpes labialis (cold sores), although less often than HSV-1.

Transmission of Herpes Simplex Virus:
Unlike viruses such as influenza, which can be transmitted through the air, Herpes Simplex Viruses require physical contact. They are frequently transmitted through mouth-to-mouth contact (in the case of HSV-1) or genital-to-genital contact (in the case of HSV-2), although other means of transmission, including hand-to-genital and mouth-to-genital contact, are possible.

How does Valtrex work?
Valtrex is selectively absorbed into cells infected with Herpes Simplex Virus. Within the cell Herpes Simplex Virus coded enzymes convert Valtrex into its active form. This active form of the drug inhibits the growth and replication of Herpes Simplex Virus by interfering with viral DNA replication.

Valtrex is preferentially taken up and converted into its active form only by Herpes Simplex Virus infected cells. Thus, Valtrex is much less toxic for normal uninfected cells.

What is Episodic Therapy and How does it Work?
With episodic therapy, you take medication for several days at the first sign of an oral or genital Herpes Simplex Virus outbreak.

Episodic therapy works by disrupting the process by which the herpes virus reproduces itself and spreads to other cells in the body. Medication, taken early in the reactivation cycle, may shorten the duration or severity of symptoms.

Is there an alternative to Episodic Therapy?
Yes. If you find that the anticipation of your next outbreak is causing you to worry constantly or if you have frequent severe outbreaks, you might want to consider suppressive therapy that involves taking medication every day to suppress outbreaks before symptoms ever appear.

Is Episodic Therapy right for me?
If you have few outbreaks, or if your outbreaks don't bother you much when they do occur, episodic therapy is probably be right for you.

How effective is Valtrex for Episodic Therapy?
In clinical trials, VALTREX shortened the healing time of genital herpes sores by 33% (four days v. six days) on average compared to placebo. Perhaps as importantly, the duration of pain associated with genital herpes was reduced by 25% (three days v. four days) in patients who received Valtrex as opposed to placebo. Valtrex also stopped viral shedding 50% (two days v. four days) faster on average than placebo. Viral shedding is the process in which virus is released from the skin during an outbreak of genital herpes.

How is Valtrex taken for Episodic Therapy?
For the first episode of infection with Herpes Simplex Virus Valtrex is taken in a dosage of 1-gram twice daily for 10 days.
- For recurrent episodes of infection with Herpes Simplex Virus Valtrex is taken in a dosage of 500-milligrams twice daily for 3 days.

What is suppressive therapy and how does it work?
With suppressive therapy, medication can be taken every day to help suppress outbreaks of Herpes Simplex Virus infection before they occur. While on suppressive drug therapy, some people can go 6 months or longer without an outbreak.

How is suppressive therapy different from Episodic Therapy?
You may now be taking medication as symptoms of an outbreak begin in order to reduce the outbreak's severity and duration. (This method of treatment is called "acute therapy" or "episodic therapy.") However, treating genital Herpes Simplex Virus infections this way does not actually affect the number of outbreaks you may experience. In contrast, suppressive therapy means taking daily medication to help suppress outbreaks before symptoms ever begin.

Is suppressive therapy right for me?
If genital herpes recurs frequently and with great severity or affects your self-esteem and confidence, you are a candidate for suppressive therapy.

How effective is Valtrex for suppressive therapy?
Over half of the patients (55%) who experienced a high frequency of outbreaks (6 or more per year) did not have a single outbreak for 6 months while taking a 1-gram VALTREX Caplet once a day.
- Only 7% of those taking placebo (sugar pill) avoided an outbreak in 6 months. By the end of 12 months, 33% of the patients taking VALTREX still had not had a single outbreak.
- compared to only 4% of those taking placebo (sugar pill). Patients with nine or fewer outbreaks showed comparable results with VALTREX 500 mg once daily. There are no data on the safety or effectiveness of suppressive therapy longer than 1 years duration.

How is Valtrex taken for suppressive therapy?
The recommended dosage of VALTREX for chronic suppressive therapy of recurrent genital herpes is 1-gram once daily.
- In patients with a history of 9 or fewer recurrences per year, an alternative dosage is 500-milligrams once daily.

If I am on therapy, can I still spread Herpes to others?
YES, no drug has been proven to prevent the spread of herpes infection to other people. You or your partner should always use condoms and avoid sexual contact during an outbreak.

Side effects of Valtrex therapy
Nausea, vomiting, headache, loss of appetite, weakness, stomach pain or dizziness may occur for the first several days after therapy has begun as your body adjusts to the medication. If any of these effects continue or become bothersome, you may have to discontinue the medication.

Precautions
On your medical history/personal profile let us know if you have any kidney disease, blood disorders or if you have any allergies. This medication should be used only if clearly needed during pregnancy. It is not know if the medicine appears in breast milk.